For treating type 2 diabetes in adults, metformin (immediate release) usually is begun at a dose of 500 mg twice a day or 850 mg once daily. The dose is gradually increased by 500 mg weekly or 850 mg every two weeks as tolerated and based on the response of the levels of glucose in the blood. Metformin là một thuốc chống đái tháo đường nhóm biguanid. Không giống sulfonylure, metformin không kích thích giải phóng insulin từ các tế bào beta tuyến tụy. Overview: Metformin is medicine you take to help keep your blood sugar from getting too high. Common side effects may include stomach problems, such as diarrhea, nausea, vomiting, stomach pain. Doctors may prescribe metformin to manage blood sugar levels in adults with type 2 diabetes. It’s typically prescribed in combination with a balanced diet and increased physical activity. If your. Metformin alone: At first, 500 milligrams (mg) two times a day taken with the morning and evening meals, or 850 mg a day taken with the morning meal. Your doctor may increase your dose if needed until your blood sugar is controlled. Metformin is an FDA-approved antidiabetic agent that manages high blood sugar levels in type 2 diabetes patients. It reduces glucose absorption from the intestines, lowers liver glucose production, and improves insulin sensitivity. Learn about side effects, how it's taken, and more of metformin. It's a generic prescription drug that's used to help manage blood sugar levels in adults and some children with type 2 diabetes.